Artikelnummer | DIA-PSA |
---|---|
Spezifität | PSA (KLK3) |
Spezies-Reaktivität | Human |
Immunogen | Rekombinantes Peptid |
Wirtsspezies | Maus |
Isotyp | IgG1/l |
Klon | HAM18 |
Klonalität (Mono-/Polyklonal) | monoklonal |
Anwendung | ELISA (Enzyme Linked Immunosorbent Assay), Immunhistochemie (IHC), Immunhistochemie (Paraffingewebe) |
Konjugation | unkonjugiert |
Verdünnung | Immunhistochemie (IHC): 1:100-1:800 |
Format | 0,05% NaN3, 2% BSA, gereinigter Antikörper (aus Kulturüberstand), in PBS (pH 7,4), Lyophilisat |
Produktlinie / Thema | Enzyme, Tumormarker/-biologie |
Zweckbestimmung | nur für Forschungszwecke |
Temperatur - Lagerung | 2-8°C |
Temperatur - Transport | bei Raumtemperatur |
Suchcode | DIAPSA, FFPE, Paraffin |
Hersteller / Marke | dianova |
Uniprot_ID | P07288 |
Gene_ID | 354 |
Alias | KLK3, Prostate Specific Antigen |
Prostate Cancer is the most common cancer in men and PSA is the most important target for management of patients diagnosed with prostate cancer. PSA is a protease exclusively produced in prostate epithelial cells and secreted into the seminal fluid. Moreover, PSA reaches the blood stream and PSA levels have been shown to be proportional to quantity of prostate epithelial cells. Therefore serum analysis has developed the most commonly used method to detect PSA for prostate cancer prevention and to monitor response to therapy. Moreover, PSA immunohistochemistry is an important and common method for routine pathological diagnosis since it allows analysis of cellular expression profiles in prostate cancer.
In diagnostic routine, PSA (HAM18) immunohistochemistry can be used in the following applications
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